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    So suggests new research that tracked changes in two genes thought to help regulate brain growth, changes that appeared well after the rise of modern humansyears ago. That the defining feature of humans — our large brains — continued to evolve as recently as 5, years ago, and may be doing so today, promises to surprise the average person, if not biologists.

    Lahn and colleagues examined two genes, named microcephalin and ASPM, that are connected to brain size. If those genes don't work, babies are born with severely small brains, called microcephaly. Using DNA samples from ethnically diverse populations, they identified a collection of variations in each gene that occurred with unusually high frequency. In fact, the variations were so common they couldn't be accidental mutations but instead were probably due to natural selection, where genetic changes that are favorable to a species quickly gain a foothold and begin to spread, the researchers report.

    Lahn offers an analogy: Medieval monks would copy manuscripts and each copy would inevitably contain errors — accidental mutations. Years later, a ruler declares one of those copies the definitive manuscript, and a rush is on to make many copies of that version — so whatever changes from the original are in this presumed important copy become widely disseminated. Scientists attempt to date genetic changes by tracing back to such spread, using a statistical model that assumes genes have a certain mutation rate over time.

    For the microcephalin gene, the variation arose about 37, years ago, about the time period when art, music and tool-making were emerging, Lahn said. For ASPM, the variation arose about 5, years ago, roughly correlating with the development of written language, spread of agriculture and development of cities, he said. Other scientists urge great caution in interpreting the research.

    That the genetic changes have anything to do with brain size or intelligence "is totally unproven and potentially dangerous territory to get into with such sketchy data," stressed Dr. Aside from not knowing what the gene variants actually do, no one knows how precise the model Lahn used to date them is, Collins added. Lahn's own calculations acknowledge that the microcephalin variant could have arisen anywhere from 14, to 60, years ago, and that the uncertainty about the ASPM variant ranged from to 14, years ago.

    Those criticisms are particularly important, Collins said, because Lahn's testing did find geographic differences in populations harboring the gene variants today. They were less common in sub-Saharan African populations, for example. That does not mean one population is smarter than another, Lahn and other scientists stressed, noting that numerous other genes are key to brain development.

    The work was funded by the Howard Hughes Medical Institute.

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    The information contained in the AP News report may not be published, broadcast, rewritten or redistributed without the prior written authority of The Associated Press. Language tree rooted in Turkey Evolutionary ideas give farmers credit for Indo-European tongues. The finding hints that farmers in what is now Turkey drove the language boom - and not later Siberian horsemen, as some linguists reckon.

    Russell Gray and Quentin Atkinson, of the University of Auckland in New Zealand use the rate at which words change to gauge the age of the tree's roots - just as biologists estimate a species' age from the rate of farmers dating site uk mutations. The differences between words, or DNA sequences, are a measure of how closely languages, or species, are related.

    Gray and Atkinson analysed 87 languages from Irish to Afghan.

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    Rather than compare entire dictionaries, they used a list of words that are found in all cultures, such as 'I', 'hunt' and 'sky'. Words are better understood than grammar as a guide to language history; the same sentence structure can arise independently in different tongues. The resulting tree matches many existing ideas about language development. Spanish and Portuguese come out as sisters, for example - both are cousins to German, and Hindi is a more distant relation to all three.

    All other Indo-European languages split off from Hittite, the oldest recorded member of the group, between 8, and 10, years ago, the pair calculates 1. Around this time, farming techniques began to spread out of Anatolia - now Turkey - across Europe and Asia, archaeological evidence shows.

    The farmers themselves may have moved, or natives may have adopted words along with agricultural technology. The conclusion will be controversial, as there is no consensus on where Indo-European languages came from. Some linguists believe that Kurgan horsemen carried them out of central Asia 6, years ago. It shows how ideas about language evolution can be tested, she says: There is lots of word-swapping within language groups.

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    English took 'skirt' from the Vikings, for example, but 'shirt' is original. Linguists must separate the shared from the swapped, as any error will affect later studies. The Kurgan might not be out of the picture entirely, says McMahon - they may have triggered a later wave of languages.

    Language-tree divergence times support the Anatolian theory of Indo-European origin. Nature,-doi: Earlier that morning I had set out on a pilgrimage to the Exalted Throne of Yahweh where Adam's god dwelt. Within an hour the farmers dating site uk and chaos of Tabriz had been left far behind, as our four-wheel drive ascended out of the alpine valley of the Adji Chay onto the plateau of the Sahand massif, with imposing volcano at its heart.

    Now I found myself at the entrance to one of our world's most extraordinary places - the troglodyte village of Kandovan. Ambling down the cobbled street - only just wide enough to take a donkey and cart - I turned up a steep side alley, all the time stalked by a clutch of free-roaming chickens.

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    The alley soon morphed into a roughly sculpted flight of steps which twisted and turned between huge canine teeth of lava. Each was a home - a dwelling from a bygone age with rickety wooden door and tiny mullioned windows.

    In this Dysneyesque landscape of cave-dwellers, I almost expected Pinocchio to appear around the next bend. Kandovan - 'The Honeycombe'. My long farmers dating site uk, starting in the research libraries of London University, had led me farmers dating site uk the Mesopotamian flood plain and on up into the mountains of Kurdistan, finally to reach the place the Book of Genesis calls the Garden of Eden.

    There is no straightforward way to explain how an Egyptologist, used to working in the dry heat of the north African deserts, should end up traversing the Zagros mountains of western Iran in search of the earthly paradise. I had begun my studies in the Departments of Egyptology and Ancient History at University College, London, with a major interest in the complex chronology of Egyptian civilisation.

    My PhD work to radically revise that chronology had inevitably drawn me into the world of biblical history - so closely bound up with the land of the pharaohs. Years of research had led me to the conclusion that many of the stories in the Old Testament were based on real historical events: But why was I now delving into the Book of Genesis - that most mythological and hoary of the biblical texts?

    Surely it would have been better to leave well alone? But that is not my way. The simple fact is that ancient stories and legends have always fascinated me and the chance to uncover the historical reality behind the greatest legend of them all was just too tempting an opportunity to pass by. The 'Temptation Seal' on display in the British Museum.

    Back in I had been sent a short, privately published paper by amateur historian, Reginald Walkerwhich proposed a location for the Garden of Eden in north-western Iran. The main thrust of Walker's argument was that the four rivers of Eden, described in Chapter Two of Genesis, were to be found in that region. All four had their sources the Bible refers to them as 'heads' around the two great salt lakes of Van and Urmia.

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    Ever since the time of the Jewish historian Josephus, a near contemporary of Christ, scholars have tried to use Genesis 2 to locate Eden. But the problem has always been the identification of the rivers themselves. The first two are no problem: The remaining two rivers, however, have always been a mystery. Clearly, in order to locate Eden precisely, we need to find the sources of all four - and that's where Walker's research comes in.

    By checking the writings of the Islamic geographers who accompanied the Arabic invasion of Persia in the 8th century, I was able to confirm that this was indeed the case. Moreover, even as late as the last century, Farmers dating site uk atlases and encyclopaedias were still naming the river as the Gaihun-Aras. The Gaihun is therefore the missing biblical Gihon.

    The fourth river - the Pishon - was more difficult to find. Walker suggested that this Hebrew West Semitic name derived from the old Iranian Uizhun, where the Iranian vowel 'U' had been converted into the Semitic labial consonant 'P'. Thus we have Uizhun to Pizhun to Pishon. Strange as it may seem, such switches do occur between the two language groups. For instance, one archaeological site in Iran is known by its Arabic West Semitic name of Pisdeli whereas its ancient Iranian name was Uishteri.

    The river Uizhun the modern Qezel Uzun - thus identified as the biblical Pishon - flows down from the mountains of Kurdistan and empties into the southern basin of the Caspian Sea. The four rivers of Eden. Bringing all this together we find that the sources of all four rivers originate in the highland area which Alexander the Great knew as Armenia and we know today as eastern Turkey and western Iran.

    A crucial line in the epic describes the envoy descending from the last of the seven mountain passes the Sumerians called them 'gates' and crossing a broad plain before arriving at the city of Aratta with its red-painted city wall. The envoy, journeying to Aratta, covered his feet with the dust of the road and stirred up the pebbles of the mountains.

    So, combining Walker's discovery of the four rivers together with the Sumerian location of Eden, it seemed as though the whereabouts of the lost Eden and its fabled garden was near to being resolved.

    I decided to set out for the ancient city of Susa burial place of Daniel of the lions' den in the south-western flood plain of Iran Iraq was off bounds for obvious reasons from where I determined to retrace the Sumerian envoy's route to paradise. Following the ancient track through the seven 'gates', I eventually reached the Miyandoab plain to the south of Lake Urmia. The journey had taken four days by car but would have taken the envoy the best part of four months by donkey.

    The edin remains today one of the lushest regions of the Middle East: This, I am sure, was the original heart of Eden which, over time, became a much wider area, including both the salt lakes and the Garden of Eden itself. The Bible describes the latter as being 'east in Eden' - in other words to the east of but still within the wider territory of Eden.

    My driver and I continued eastwards, between the south-eastern shore of Lake Urmia and the towering volcanic peak of Mount Sahand. An hour's drive along the highway brought us into a long west to east valley, the slopes of which were terraced with 'every kind of tree' smothered in spring blossom God planted a garden in Eden, which is in the east, and there he put the man he had fashioned.

    From the soil, God caused to grow every kind of tree, enticing to look at farmers dating site uk good to eat. The nearest mountain to the north glowed bright red in the low evening light - a pile of pure red ochre. At its foot sprawled the regional capital of Tabriz, squatting at the centre of the valley where Adam and Eve whoever they were once lived according to biblical tradition. The first thing which came to mind was paradise lost. Nothing of the earthly garden and its settlement could have survived beneath these bustling streets.

    But then, away from the city, I soon discovered that there was much that remains of Adam's Neolithic culture. Paradise Lost - the sprawling city of Tabriz. This was the region where Man first began to settle down to sedentary life; where he learnt to domesticate animals and plant his crops; and where he began to bury his dead in graves, the bones painted in red-ochre.

    Adam's name means the 'red-earth' man.
    The children were inconsolable. Mute with shock and fighting back tears, they huddled beside their mother as friends and neighbours prepared their father's body for cremation on a blazing bonfire built on the cracked, barren fields near their home.

    As flames consumed the corpse, Ganjanan, 12, and Kalpana, 14, faced a grim future. While Shankara Mandaukar had hoped his son and daughter would have a better life under India's economic boom, they now face working as slave labour for a few pence a day. Landless and homeless, they will be the lowest of the low. A farmer and child in India's 'suicide belt' Shankara, respected farmer, loving husband and father, had taken his own life. Less than 24 hours earlier, facing the loss of his land due to debt, he drank a cupful of chemical insecticide.

    Unable to pay back the equivalent of two years' earnings, he was in despair. He could see no way out. There were still marks in the dust where he had writhed in agony. Other villagers looked on - they knew from experience that any intervention was pointless - as he lay doubled up on the ground, crying out in pain and vomiting.

    Moaning, he crawled on to a bench outside his simple home miles from Nagpur in central India. An hour later, he stopped making any noise. Then he stopped breathing. At 5pm on Sunday, the life of Shankara Mandaukar came to an end. As neighbours gathered to pray outside the family home, Nirmala Mandaukar, 50, told how she rushed back from the fields to find her husband dead.

    The mental anguish was too much. We have lost everything. Of course, famine and pestilence are part of India's ancient story. But the death of this respected farmer has been blamed on something far more modern and sinister: Shankara, like millions of other Indian farmers, had been promised previously unheard of harvests and income if he switched from farming with traditional seeds to planting GM seeds instead.

    Prince Charles has set up charity Bhumi Vardaan Foundation to address the plight of suicide farmers Beguiled by the promise of future riches, he borrowed money in order to buy the GM seeds.

    But when the harvests failed, he was left with spiralling debts - and no income. So Shankara became one of an estimatedfarmers to take their own life as a result of the ruthless drive to use India as a testing ground for genetically modified crops.

    The crisis, branded the 'GM Genocide' by campaigners, was highlighted recently when Prince Charles claimed that the issue of GM had become a 'global moral question' - and the time had come to end its unstoppable march.

    Speaking by video link to a conference in the Indian capital, Delhi, he infuriated bio-tech leaders and some politicians by condemning 'the truly appalling and tragic rate of small farmer suicides in India, stemming Ranged against the Prince are powerful GM lobbyists and prominent politicians, who claim that genetically modified crops have transformed Indian agriculture, providing greater yields than ever before.

    The rest of the world, they insist, should embrace 'the future' and follow suit. So who is telling the truth? To find out, I travelled to the 'suicide belt' in Maharashtra state. What I found was deeply disturbing - and has profound implications for countries, including Britain, debating whether to allow the planting of seeds manipulated by scientists to circumvent the laws of nature.

    For official figures from the Indian Ministry of Agriculture do indeed confirm that in a huge humanitarian crisis, more than 1, farmers kill themselves here each month. Simple, rural people, they are dying slow, agonising deaths. Most swallow insecticide - a pricey substance they were promised they would not need when they were coerced into growing expensive GM crops. It seems that many are massively in debt to local money-lenders, having over-borrowed to purchase GM seed. Pro-GM experts claim that it is rural poverty, alcoholism, drought and 'agrarian distress' that is the real reason for the horrific toll.

    But, as I discovered during a four-day journey through the epicentre of the disaster, that is not the full story.

    A Farmers dating site uk protester sprays milk-based paint on a Monsanto research soybean field near Atlantic, Iowa In one small village I visited, 18 farmers had committed suicide after being sucked into GM debts. In some cases, women have taken over farms from their dead husbands - only to kill themselves as well.

    Latta Ramesh, 38, drank insecticide after her crops failed - two years after her husband disappeared when the GM debts became too much. She left her ten-year-old son, Rashan, in the care of relatives. Village after village, families told how they had fallen into debt after being persuaded to buy GM seeds instead of traditional cotton seeds.

    The price difference is staggering: But GM salesmen and government officials had promised farmers that these were 'magic seeds' - with better crops that would be free from parasites and insects. Indeed, in a bid to promote the uptake of GM seeds, traditional varieties were banned from many government seed banks.

    The authorities had a vested interest in promoting this new biotechnology. Desperate to escape the grinding poverty of the post-independence years, the Indian government had agreed to allow new bio-tech giants, such as the U. In return for allowing western companies access to the second most populated country in the world, with more than one billion people, India was granted International Monetary Fund loans in the Eighties and Nineties, helping to launch an economic revolution.

    But while cities such as Mumbai and Delhi have boomed, the farmers' lives have slid back into the dark ages. Though areas of India planted with GM seeds have doubled in two years - up to 17 million acres - many famers have found there is a terrible price to be paid.

    Far from being 'magic seeds', GM pest-proof 'breeds' of cotton have been devastated by bollworms, a voracious parasite. Nor were the farmers told that these seeds require double the amount of water. This has proved a matter of life and death. With rains failing for the past two years, many GM crops have simply withered and died, leaving the farmers with crippling debts and no means of paying them off.

    Having taken loans from traditional money lenders at extortionate rates, hundreds of thousands of small farmers have faced losing their land as the expensive seeds fail, while those who could struggle on faced a fresh crisis.

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    When crops failed in the past, farmers could still save seeds and replant them the following year. But with GM seeds they cannot do this. That's because GM seeds contain so- called 'terminator technology', meaning that they have been genetically modified so that the resulting crops do not produce viable seeds of their own. As a result, farmers have to buy new seeds each year at the same punitive prices.

    For some, that means the difference between life and death. Take the case of Suresh Bhalasa, another farmer who was cremated this week, leaving a wife and two children. As night fell after the ceremony, and neighbours squatted outside while sacred cows were brought in from the fields, his family had no doubt that their troubles stemmed from the moment they were encouraged to buy BT Cotton, a geneticallymodified plant created by Monsanto.

    Our crop failed twice. My husband had become depressed. He went out to his field, lay down in the cotton and swallowed insecticide. He sent his children to school and paid his taxes. They sell us the seeds, saying they will not need expensive pesticides but they do. We have to buy the same seeds from the same company every year. It is killing us. Please tell the world what is happening here. But pointing out that cotton production had doubled in the past seven years, a spokesman added that there are other reasons for the recent crisis, farmers dating site uk as 'untimely rain' or drought, and pointed out that suicides have always been part of rural Indian life.

    During the course of my inquiries in Maharastra, I encountered three 'independent' surveyors scouring villages for information about suicides. They insisted that GM seeds were only 50 per cent more expensive - and then later admitted the difference was 1, per cent. A Monsanto spokesman later insisted their farmers dating site uk is 'only double' the price of 'official' non-GM seed - but admitted that the difference can be vast if cheaper traditional seeds are sold by 'unscrupulous' merchants, who often also sell 'fake' GM seeds which are prone to disease.

    With rumours of imminent government compensation to stem the wave of deaths, many farmers said they were desperate for any form of assistance. India's farmers are also starting to fight back.

    As well as taking GM seed distributors hostage and staging mass protests, one state government farmers dating site uk taking legal action against Monsanto for the exorbitant costs of GM seeds.

    He just said it was better to die. They will lose their land, joining the hordes seen begging in their thousands by the roadside throughout this vast, chaotic country. Here in the suicide belt of India, the cost of the genetically modified future is murderously high.

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